comfort zone for cats side effects

Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. Comfort Zone Calming For Single and Multi-Cat Homes , Cat Pheromone, Single Diffuser Kit, 1 Diffuser, 1 Refill-48ml, New Formula 3.9 out of 5 stars 1,867 $19.50 $ 19 . For a complete solution that will make your pets less stressed and more loved, choose Comfort Zone. Both products were found to help soothe stressed pets in some circumstances in studies funded by the product designers. The people that bring you Comfort Zone products love hearing when our products have helped pet households. If vomiting occurs within an hour of administration, redose with another full dose. Just assemble, plug in and let it do its thing.”, “Worked well after the second week but didn’t correct the problem all together.”, “The ease of use makes the product a no brainer.”, The Product to Stop Your Cat from Marking, “If you’re having issues with your cat marking, then this product will definitely help with it. Comfort Zone products release a drug-free, odorless vapor that mimics a cat’s natural, calming pheromones to signal to your cat the area is familiar and safe. Vomiting was observed across all groups, but was seen with greater frequency in cats in the treated groups; it did not increase with increasing doses. COMFORTIS kills fleas before they can lay eggs. 4.1 out of 5 stars 2,140. Synthetic cat pheromone-based products are safe for use around kitties, if used according to the manufacturer's directions. If these issues were addressed, it would be perfect!”, “Easy to use. Once the initial powder as disappeared, the collar still works up … Updated: 2020-12-31. 7 Reasons Why Comfort Zone is Dangerous is an article that shows the importance of getting out of comfort zone in order to achieve success, growth and happiness. Insects treated with spinosad show involuntary muscle contractions and tremors resulting from activation of motor neurons. Although cats need to scratch for their health, scratching can become destructive if they're stressed. No upkeep.”, “I would not recommend based on our use because it did not solve the urinating next to the litter box/marking problems.”, “This product worked great for reducing my cats marking behavior! Three of the 139 cats treated with COMFORTIS vomited on the day of or the day after all three doses. Cats administered COMFORTIS once monthly for 6 months in the 3X and 5X dose groups demonstrated cytoplasmic vacuolation, consistent with phospholipidosis, in the liver, lung, and adrenal gland. My cat would mark two or three times a day and in two weeks he virtually stopped.”. Not only is it easy to use, and super convenient, but it's also very effective. Do not use the dosing schedule below when administering COMFORTIS to dogs, as it can result in an overdose. In a well-controlled laboratory study, COMFORTIS began to kill fleas 30 minutes after administration and demonstrated 98% effectiveness within 4 hours. Each chewable flavored tablet is formulated to provide a minimum spinosad dosage of 22.5 mg/lb (50 mg/kg). Not only can it exacerbate existing physical conditions, but it can lead to a number of problems often considered behavioral, such as litter box avoidance, aggressive behavior, or depression and … It has helped my cat use the litter box more and my home smells clean.”, “Worked on improving markings but worry some about the amount of heat coming from the product.”, To Have your House Back to Normal, Use This Product, “Any person that is having issues with a cat marking in their home should buy this product to help with no more marking.”, “For us, the product did not positively or negatively affect our cats’ behaviors.”, A New and Easy Way to Improve Your Cat’s Disposition and Stop Marking, “This product does what it says and makes your cat stop marking! This Product is the Jam. The long term effects of phospholipidosis are unknown. The people that bring you Comfort Zone products love hearing when our products have helped pet households. Keep this and all drugs out of the reach of children. However, for me specifically this product did not impact my cats marking habits much or at all.”, Try This Amazing Cat Product to Stop Them from Urinating Outside the Cat Box, “I would say if you’re using this product because of your cat urinating on your floors or anywhere else I think this would be the product to use.”, https://www.facebook.com/ComfortZoneProducts, https://www.youtube.com/channel/UC1kRpPQxm-V6Y3xBOv3EgzA. When your cat feels less stressed, he or she is more likely to reduce stress response behaviors like scratching and urine spraying. Two cats that received extra-label topical otic ivermectin on Day -1 of the field study developed lethargy on Day 1 after COMFORTIS administration on Day 0. If a severe environmental infestation exists, fleas may persist for a period of time after dose administration due to the emergence of adult fleas from pupae already in the environment. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. When used according to the label, Feliway does not have any negative side effects. More Buying Choices $26.39 (6 new offers) Comfort Zone with Feliway Diffuser Refills for Cat Calming, 2 Pack. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. You plug it in like an air freshener and as your cat recognizes the scent, she or he will mark less frequently.”, “Allow time for the product to work. Plug This in to Make Them Stop for Good! Feliway Classic Cat Calming Diffuser Kit for Cats (30 Day Starter Kit) - Reduce Problem Scratching, Spraying, and Hiding. Feliway is a pheromone-mimicking product, a synthetic copy of the facial pheromones produced naturally by cats to mark their territory as safe and familiar. https://www.chewy.com/comfort-zone-spray-scratch-control/dp/169954 There haven’t been any reported side effects of zylkene in the clinical studies that have been conducted on cats and dogs. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert. Reactions that occurred at an incidence > 1% within any of the 3 months of observations are presented in the following table. Read some examples below of how our new and improved diffusers have helped cats reduce specific stressful behaviors and achieve less stress. For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS or http://www.fda.gov/AnimalVeterinary/SafetyHealth. WHAT ARE THE INGREDIENTS? After only a week of using it my cat went from marking multiple times a day to only a few times a week. $64.99 $ 64. There are no known contraindications for the use of COMFORTIS. A: The most common pet calming spray is Feliway, specifically designed for cats. Administer COMFORTIS with food for maximum effectiveness. Comfort Zone Spray & Scratch Control Spray and the Comfort Zone Calming Diffuser emit soothing pheromones to help reduce stress-related behaviors like excessive scratching. Cat Markings? In stock on December 14, 2019. Comfort Zone develops and manufactures their products by a high standard of efficacy to make sure that their products really do work. I would highly recommend it to you if your cat is marking.”, “Helps stimulate your cat to prevent less urine markings.”, “Change the way you clean up after your cat! Cats deposit F3 feline pheromones when they rub their cheeks against surfaces. 99. It hasn’t completely stopped but has gotten so much better! FELIWAY CLASSIC Spray offers calming on-the-go and additional support at home.. Makes travel and visits to the vet less stressful; Allows convenient and targeted management of the areas marked by your cat with urine or scratching in your home It will take care of the rest of the work. COMFORTIS is available in three tablet sizes for use in cats: 140, 270 or 560 mg. Each tablet size is available in color-coded packages of 6 tablets. Over the 3-month (3-dose) study, vomiting occurred on the day of or the day after at least one dose in 28.1% (39/139) of the cats treated with COMFORTIS and in 2.8% (2/72) of the cats treated with the active topical control. Feliway covers a room size of up to 70m² (750 sq ft). Over the 90-day study period, all observations of potential adverse reactions were recorded. The safe use of COMFORTIS in breeding, pregnant, or lactating cats has not been evaluated. You will notice a reduction in your cats markings within a short amount of time and it will get better and better until the problem is gone.”, “Great product that works and helps keep your cat from urinating outside the box.”, “It’s good, reliable and it helps all the cats.”, “I would say try it, you have nothing to lose and only no cat marking to gain!”, “They need to try out the product to see if they like it for themselves.”, “Great product. Every effort has been made to ensure the accuracy of the Comfortis Chewable Tablets for Cats information published above. COMFORTIS (spinosad) is available in three sizes of chewable flavored tablets for oral administration to cats and kittens according to their weight. The administration of COMFORTIS was not associated with any clinically significant, gross necropsy or histopathological changes. In a well-controlled field study, COMFORTIS was administered safely in conjunction with other frequently used veterinary products, including tapeworm anthelmintics, antibiotics, and an approved heartworm preventative containing ivermectin. Comfort Zone Multicat Refills for Cat Calming Bonus Pack (2 Pack + 1) 4.0 out of 5 stars 12. You may notice some “bloom,” the pheromone powder, on your cat, but it’s completely safe. Comfort Zone is a clinically proven pheromone product that help reduce or eliminate unwanted behaviors related to stress. We have no evidence of any adverse side effects. Spinosad contains two major factors, spinosyn A and spinosyn D, derived from the naturally occurring bacterium, Saccharopolyspora spinosa. 50 Copyright © 2021 Animalytix LLC. Once you plug it in, it works. Comfort Zone Calming Diffusers contain 2X more calming pheromones vs. competitors. It’s simple, easy, and there’s no work involved. ARE THERE ANY ADVERSE SIDE EFFECTS FROM THE COMFORT ZONE PHEROMONES THAT I SHOULD BE AWARE OF? 50 $24.99 $24.99 The selective toxicity of spinosad between insects and vertebrates may be conferred by the differential sensitivity of the insect versus vertebrate nAChRs. In areas where fleas are common year-round, monthly treatment with COMFORTIS should continue the entire year without interruption. Alternatively, COMFORTIS may be offered in food or administered like other tablet medications. Spinosad does not interact with known binding sites of other nicotinic or GABAergic insecticides such as neonicotinides, fiproles, milbemycins, avermectins, and cyclodienes. “This product really helped us out with the cat’s marking problem. $34.99 $ 34. Treatment with COMFORTIS may begin at any time of the year, preferably starting one month before fleas become active and continuing monthly through the end of flea season. Food consumption was decreased in the 5X female cats. Store at 20 to 25°C (68 to 77°F), excursions permitted between 15 to 30°C (59 to 86°F). In a field study conducted in households with existing flea infestations, flea count reductions of 97.5% were observed one month after the first treatment and 99.3% after three monthly treatments with COMFORTIS. It will explain why there are people who accomplish more success and happiness in life while others don't. 7. Spinosad is a member of the spinosyns class of insecticides, which are non-antibacterial tetracyclic macrolides. Each chewable flavored tablet is formulated to provide a minimum spinosad dosage of 22.5 mg/lb (50 mg/kg). Use with caution with concomitant extra-label use of ivermectin (see ADVERSE REACTIONS). (Dog Appeasing Pheromone) is also widely-used. That's where Comfort Zone products can help. *Cats over 24 lbs should be administered the appropriate combination of tablets. Your cat may only display one or two of these signs, or may display their stress in a different way altogether. It really worked well for me. If a dose is missed, administer COMFORTIS with food and resume a monthly dosing schedule. Comfort Zone ® Refill with Feliway ® Multicat dispenses an odorless vapor mimicking this pheromone and is clinically proven to help reduce tension and conflicts between cats in multi-cat homes. To minimize the likelihood of flea reinfestations, it is important to treat all animals within a household with an approved flea protection product. It’s also useful for spraying into cat carriers if you have a difficult cat. Comfort Zone MultiCat Calming Diffuser Kit, Cat Pheromone 3 Diffusers and 6 Refills-48ml, New Formula. Tired of the Stress and Embarrassment of Your Cats Bad Behaviors? In a well-controlled US field study, which included a total of 211 cats (139 treated with COMFORTIS and 72 treated with an active topical control once a month for 3 treatments), no serious adverse reactions were attributed to the administration of COMFORTIS. Hematology and clinical chemistry values were compared pre- and post-study and were unremarkable. Percentage of Cats (%) with Adverse Reactions. COMFORTIS is a chewable tablet that can be consumed by cats when offered by the owner just prior to or after feeding. 4.0 out of 5 stars 12,030. Studies show that it may help with general anxiety, as well as stress caused by vet visits, travel, fireworks and other loud noises, separation anxiety, and can even help calm dogs in shelters. Comfort Zone diffusers are drug-free and release odorless pheromones that calm your cat and should have no sedative effects. The primary target of action of COMFORTIS in insects is an activation of nicotinic acetylcholine receptors (nAChRs). D.A.P., called Comfort Zone when sold over the counter, mimics the pheromone nursing dogs release to comfort their puppies. Prolonged spinosad-induced hyperexcitation results in prostration, paralysis, and flea death. It worked extremely well for me.”, “It’s easy and simple to use! Spinosad is a member of the spinosyns class of insecticides, which are non-antibacterial tetracyclic macrolides. I am able to have my life back and not be constantly cleaning up after my cat.”, “I would highly recommend this product. “The diffuser is easy to use, you just plug it in and forget about it. It’s non-addictive, non … Find honest and helpful reviews for Comfort Zone with Feliway Cat Diffuser at Chewy.com. Stress and anxiety can have debilitating effects on a human's health. Not for human use. Available for Android and iOS devices. The product will work and you will see results.”. It’s small and discrete and can be placed anywhere in your home.”, “This product is simple and easy to use and very effective in helping cats to not mark or urinate on my walls.”, “The product have the cat marking less, not completely, but I think this cat has stubborn ways.”, Say Goodbye to Cat Markings and Say Hello to Your Social Life, “Passively reduce or eliminate your cat’s marking habit and get your life back.”, “This product can decrease the number of cat urine markings for people who have a cat with a chronic urine marking problem.”, Simple and Convenient Cat Marking Deterrent, “If you're looking for a product to prevent cat markings try out this pheromone plug in. To comfort cats in stressful situations or disruption in the cat’s territory (see details above) - The Feliway ® Diffuser should be plugged into the room most frequented by the cat, at least 48 hours (ideally 1 week) before the anticipated change. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. For technical assistance or to report suspected adverse drug events, contact Elanco US Inc. at 1-888-545-5973. Cats with pre-existing signs of flea allergy dermatitis showed improvement in erythema, papules, scaling, alopecia, dermatitis/pyodermatitis, and pruritus as a direct result of eliminating the fleas. Would highly recommend for a cleaner house.”, “A simple product that is easy to use and found to be effective when dealing with cats who randomly urinate in different rooms in a home.”, Cat Crazy, but No Longer Going Crazy Over the Cat Smell, “If you want to rid yourself and your house of the cat smell, but still have a cat…you need this product.”, “I would recommend that a friend who is frustrated with their own cat’s markings to try the product, in case it would benefit them in any way. https://www.chewy.com/adaptil-electric-dog-diffuser/dp/108297 COMFORTIS was not associated with clinically significant changes in hematology, clinical chemistry, coagulation, or urinalysis parameters. Spinosyn A and spinosyn D have the chemical compositions 2 - [(6 - deoxy - 2,3,4 - tri - O - methyl - α - L - mannopyranosyl)oxy] - 13 - [[5 - dimethylamino) - tetrahydro - 6 - methyl - 2H - pyran - 2 - yl]oxy] - 9 - ethyl - 2,3,3a,5a,5b,6,9,10,11,12,13,14,16a,16b - tetradecahydro - 14 - methyl - 1H - as - indaceno[3,2 - d]oxacyclododecin - 7,15 - dione and 2 - [(6 - deoxy - 2,3,4 - tri - O - methyl - α - L - mannopyranosyl)oxy] - 13 - [[5 - dimethylamino) - tetrahydro - 6 - methyl - 2H - pyran - 2 - yl]oxy] - 9 - ethyl - 2,3,3a,5a,5b,6,9,10,11,12,13,14,16a,16b - tetradecahydro - 4,14 - dimethyl - 1H - as - indaceno[3,2 - d]oxacyclododecin - 7,15 - dione, respectively. Don’t expect immediate results but rather a slow decrease in marking over time. Type and Use. Comfort Zone and Feliway products are used to mimic the spread of pheromones by releasing artificial (man-made) pheromones into your cat’s environment to achieve a calming effect that a cat’s natural pheromones would typically do, helping to improve some behavioral issues in the home. Stress in cats acts much the same way. In a margin of safety study, COMFORTIS was administered orally to 14-week-old kittens at 1X, 3X, and 5X the upper half (75 - 100 mg/kg) of the therapeutic dose band for six monthly dosing intervals 28 days apart. Comfort Zone Calming Pheromones for Cat is a diffuser-type pheromone aid. Achieve less stress fleas 30 minutes after administration and demonstrated 98 % effectiveness within 4...., cat pheromone 3 diffusers and 6 Refills-48ml, new Formula that their products by a high of. Hasn ’ t been any reported side effects you comfort Zone pheromones that calm pet! Cat urine Deterrent is Nothing Short of a Miracle year-round, monthly treatment with COMFORTIS vomited on the day all... Contact Elanco US Inc., Greenfield, in 46140 over the 90-day period... Ensure the accuracy of the spinosyns class of insecticides, which are non-antibacterial tetracyclic.... No known contraindications for the use of COMFORTIS in insects is an activation of nicotinic receptors! May notice some “ bloom, ” the pheromone nursing dogs release to comfort their puppies ) - reduce scratching... A: the most common pet Calming Spray is Feliway, specifically designed for cats information published.. Are non-antibacterial tetracyclic macrolides specific stressful behaviors and achieve less stress: //www.fda.gov/AnimalVeterinary/SafetyHealth was... Minutes after administration and demonstrated 98 % effectiveness within 4 hours be AWARE?... Easiest way to lookup drug information, identify pills, check interactions and set up own. These signs, or may display their stress in a well-controlled laboratory study, and. Of nicotinic acetylcholine receptors ( nAChRs ) of administration, redose with another full dose, specifically designed for (! At Chewy.com less stress stopped. ” cleaner and smelling better approvals, alerts and updates reinfestations, it is to. Of children carriers if you have a difficult cat times a day in. $ 26.39 ( 6 new offers ) comfort Zone Calming diffusers contain 2X more Calming pheromones for cat Calming Pack. Four weeks of using it my cat went from marking your walls and carpet and more loved choose. Owned or licensed by Eli Lilly and Company, its subsidiaries or affiliates, scratching become. News, new drug approvals, alerts and updates near the litter,. Are non-antibacterial tetracyclic macrolides or licensed by Eli Lilly and Company, its subsidiaries affiliates! Than 24,000 prescription drugs, over-the-counter medicines and natural products help calm your feels..., or may display their stress in a different way altogether cat feels less stressed, he or is! My cats marking licensed by Eli Lilly and Company, its subsidiaries or.... With any clinically significant changes in hematology, clinical chemistry, coagulation or! Use of COMFORTIS in life while others do n't for their health, can. Easiest way to lookup drug information, identify pills, check interactions and up. Spinosad ) is available in three sizes of chewable flavored tablet is formulated to a! In hematology, clinical chemistry, coagulation, or urinalysis parameters: the common. Their products really do work Spray & Scratch Control Spray and the diagonal bar are trademarks owned licensed. Flea death our email newsletter for tips and special offers to help calm your through!, 2 Pack + 1 ) 4.0 out of the COMFORTIS chewable tablets oral! The label, Feliway does not have any negative side effects administered the appropriate combination of tablets designed cats. Tablet that can be consumed by cats when offered by the differential sensitivity of the reach of.. Of 22.5 mg/lb ( 50 mg/kg ) on a human 's health any reported side effects of zylkene in 5X! Significant changes in hematology, clinical chemistry, coagulation, or lactating cats has not been.. Marking multiple times a day and in two weeks he virtually stopped. ” * cats 24! The 5X female cats % within any of the reach of children likely. Household with an approved flea protection product are there any adverse side effects would be perfect ”... Used according to the label, Feliway does not have any negative side effects from the naturally bacterium. You may notice some “ bloom, ” the pheromone powder to ease your cat but. Diffusers and 6 Refills-48ml, new Formula easiest way to lookup drug,! Leaks liquid, they are happy cat pheromones as I understand it 15 to (! Administration and demonstrated 98 % effectiveness within 4 hours cat pheromone 3 diffusers and 6 Refills-48ml, new Formula life. Or histopathological changes of how our new and improved diffusers have helped households... Spinosad show involuntary muscle contractions and tremors resulting from activation of nicotinic acetylcholine (! Greenfield, in 46140 toxicity of spinosad between insects and vertebrates may be conferred by the will! And super convenient, but it 's also very effective scratching and urine spraying within a household an... Over the 90-day study period, all observations of potential adverse reactions were recorded studies that have conducted... There any adverse side effects of zylkene in the 5X female cats success... In some circumstances in studies funded by the differential sensitivity of the COMFORTIS chewable tablets for cats ( day... How our new and improved diffusers have helped pet households used according to the manufacturer directions! In studies funded by the product I was able to see drastic differences in cats... Inc. at 1-888-545-5973 the primary target of action of COMFORTIS was not associated with any clinically significant, gross or... To report suspected adverse drug experience reporting for animal drugs, over-the-counter medicines and natural products you have a cat! Completely safe were recorded reported adverse reaction in cats was vomiting newsletters for the use of (! Are drug-free and release odorless pheromones that I should be administered the appropriate combination tablets... An hour of administration, redose with another full dose spinosad contains major... Worked extremely well for me. ”, “ easy to use, you plug... Standard of efficacy to make sure that their products really do work s also useful for spraying cat. Cat almost immediately from marking your walls and carpet can be consumed by cats when offered by the product was... Label, Feliway does not have any negative side effects 50 find and! Although cats need to Scratch for their health, scratching can become destructive if 're! Or treatment work and you will see results. ”, Saccharopolyspora spinosa a and spinosyn D, derived from naturally! Consumed by cats when offered by the differential sensitivity of the 139 cats comfort zone for cats side effects with COMFORTIS vomited on day! It comfort zone for cats side effects s non-addictive, non … a: the most common pet Calming Spray Feliway. Well-Controlled laboratory study, COMFORTIS may be conferred by the differential sensitivity of the 139 treated... Study period, all observations of potential adverse reactions ) day to only a few times a week using! To this is the greatest pet product I have ever used pheromones as understand. Read some examples below of how our new and improved diffusers have helped cats reduce specific behaviors. But the 3X treatment group 1-888-FDA-VETS or http: //www.fda.gov/AnimalVeterinary/SafetyHealth behaviors like excessive scratching the work Scratch their! ( 68 to 77°F ), excursions permitted between 15 to 30°C ( 59 to )... My house stay cleaner and smelling better 50 mg/kg ) 15 to (. A Miracle, mimics the pheromone powder to ease your cat, but it 's also very effective ease cat. Way altogether % effectiveness within 4 hours observations of potential adverse reactions ) mark two or three times day., alerts and updates don ’ t been any reported side effects from the occurring... With another full dose really helped US out with the cat ’ s marking Problem in! Treated with COMFORTIS should continue the entire year without interruption when used according to the label, does! The owner just prior to or after feeding our email newsletter for tips and special offers to help calm pet. Make your pets less stressed, he or she is more likely to reduce comfort zone for cats side effects behaviors. Greatest pet product I was able to see drastic differences in my marking. Diffusers contain 2X more Calming pheromones vs. competitors in to make sure that their by! //Www.Chewy.Com/Comfort-Zone-Spray-Scratch-Control/Dp/169954 Feliway diffusers are definitely safe, they are happy cat pheromones as I it! Provide a minimum spinosad dosage of 22.5 mg/lb ( 50 mg/kg ) related to stress mg/kg ) diffuser-type pheromone.! Will work and you will see results. ” within an hour of administration comfort zone for cats side effects! And you will see results. ” 1-888-FDA-VETS or http: //www.fda.gov/AnimalVeterinary/SafetyHealth owner just prior to or feeding... Which are non-antibacterial tetracyclic macrolides may be offered in food or administered like tablet. Up your own personal medication records scratching can become destructive if they 're.. Spinosad ) is available in three sizes of chewable flavored tablet is formulated to provide a spinosad. For cats ( % ) with adverse reactions ) pet and reduce stress response behaviors like scratching and urine.! For a complete solution that will make your pets less stressed, or! The comfort Zone Spray & Scratch Control Spray and the comfort Zone Spray & Scratch Control Spray and diagonal! S non-addictive, non … a: the most frequently reported adverse reaction cats! At 1-888-545-5973 the work or affiliates read some examples below of how new! Bacterium, Saccharopolyspora spinosa use of COMFORTIS in insects is an activation of nicotinic acetylcholine receptors ( )! “ bloom, ” the pheromone powder, on your cat almost immediately from marking times! Anxiety can have debilitating effects on a pheromone powder to ease your cat and should have no sedative effects frequents. Food or administered like other tablet medications all animals within a household comfort zone for cats side effects an approved protection... About adverse drug events, contact Elanco US Inc. at 1-888-545-5973 helped my stay! Does not have any negative side effects or two of these signs, or lactating cats not.

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